You may not have heard of visceral leishmaniasis, onchocerciasis, or lymphatic filariasis, and there is a reason for that. These diseases, part of a group of infections called neglected tropical diseases (NTDs), impact more than a billion people on the planet in countries other than ours. Despite the consolation that these often grotesque illnesses are "out of sight, out of mind," some of these infections are quietly taking their toll in some southern communities of the US.