Superbugs

Unfortunately, the very places we go to receive health care put us at risk for becoming infected with superbugs, bacteria exposed to so many antibiotics that they have become immune to their effects. Clostridium difficile (C. diff) is one such bacteria. It causes inflammation of the colon and rampant diarrhea that can have life-threatening consequences. Part of its virulence lies in the tough spores formed by the bacteria. They are responsible for starting infections in the colon and for...

Antibiotics are one of our main weapons against infections. The problem is that many bacteria are becoming resistant to most of the antibiotics we use to treat them, and those 'superbugs' have created an urgent threat to our global health. A research group found a new way to hit a well known bacterial target and have developed a drug to hit it.

New research reveals how E. coli bacteria construct elaborate and effective tunnels to pump unwanted molecules like antibiotics and other toxins out of cells. The discovery could help us better understand how antibiotic resistance occurs and give us a leg-up to beat them at their own game.

Significant strides have been in the race to find antibiotics to treat superbug infections — those caused by bacteria resistant to the antibiotics used to treat them. Now, an international team of scientists has discovered a new antibiotic produced by a microbe found in Italian soil.

What do Leo Tolstoy (writer), Beethoven (composer), Paul Gaugin (artist), and Adolf Hitler (politician) have in common? They are all considered to have suffered from the sexually transmitted disease syphilis.

Could your fever, body aches, cough, and sore throat be the flu? Soon, finding out may not involve a trip to the doctor.

Even though the Ebola virus was discovered as recently as 1976, over 30,000 people have been infected since, and half have died a horrible death. Since there's no way to cure the infection, the world desperately needs a way to prevent it — and the five similar viruses in its family, the ebolaviruses.

The bacteria Klebsiella pneumoniae is a bad actor known for being antibiotic-resistant and causing a variety of serious infections in hospitals, including pneumonia, surgical site wounds, and meningitis. K. pneumoniae is something you do not want to encounter if you have a compromised immune system.

The evolution of our infection-fighting systems may have something to teach modern scientists. That's what a group from the University of Granada in Spain found when they studied a protein that's been around for over four billion years. Their work, by senior author José Sánchez-Ruiz and colleagues in the Department of Physical Chemistry, was published in the journal Cell Reports.

On October 17, 1943, a story in the New York Herald Tribune read "Many laymen — husbands, wives, parents, brothers, sisters, friends — beg Dr. Keefer for penicillin," according to the American Chemical Society. Dr. Chester Keefer of Boston was responsible for rationing the new miracle drug, penicillin.

Antibiotics used to prevent diseases in livestock are creating a world of hurt for humans and the soil we depend on for food. Bacterial resistance to antibiotics is a global health issue. The overuse, underuse, and poor use of these life-saving drugs is rapidly removing them as a treatment option for serious infections in humans—plus bacteria are naturally adaptive.

In the ongoing search to find better ways to use antibiotics, an extract made from maple syrup has some surprisingly important medical benefits.

Phase 2 of a Zika vaccine trial began in the United States this week, along with Central and South America.

Antibiotic use in infants has been associated with a host of childhood conditions later in life. Yet when an infection is suspected in a newborn, usually a sample of their blood is drawn to check for the presence of bacteria and 5 to 8 percent of them receive antibiotics while the diagnosis is pending.

We usually associate Salmonella bacteria with a dangerous type of food poisoning, but they actually are pretty good at seeking out tumors. That trait made the bacteria a great candidate to deliver a protein that would help knock tumors out.

The pathogen referred to as a "nightmare bacteria" is quietly adapting and spreading faster than anticipated.

Lighthouses and signal fires may have been the first social media. Without the ability to share language, a distant light meant "humans here." A new study from the University of California, San Diego, finds that bacteria can also send out a universal sign to attract the attention of their own, and other bacterial species.

Cholera may be rare in the US, but cases of the disease have increased worldwide since 2005, particularly in Africa, southeast Asia, and Haiti. An estimated 3 to 5 million people are infected, and more than 100,000 die from the disease globally each year, mostly from dehydration.