Unfortunately, the very places we go to receive health care put us at risk for becoming infected with superbugs, bacteria exposed to so many antibiotics that they have become immune to their effects. Clostridium difficile (C. diff) is one such bacteria. It causes inflammation of the colon and rampant diarrhea that can have life-threatening consequences. Part of its virulence lies in the tough spores formed by the bacteria. They are responsible for starting infections in the colon and for...
The growing list of dangerous antibiotic resistant organisms has just acquired three new members. Researchers have discovered three new species of Klebsiella bacteria, all of which can cause life-threatening infections and have genes that make them resistant to commonly used antibiotics.
During the millions of years they've been on earth horseshoe crabs have developed a trick that can save our lives even now — and may be especially useful in the fight against healthcare-associated infections.
Antibiotics are one of our main weapons against infections. The problem is that many bacteria are becoming resistant to most of the antibiotics we use to treat them, and those 'superbugs' have created an urgent threat to our global health. A research group found a new way to hit a well known bacterial target and have developed a drug to hit it.
Staphylococcus aureus is a widespread bacteria — about a third of us have it on our body right now — usually in our nose or on our skin. And it probably isn't causing an infection. But, about 1% of people who have Staphylococcus aureus present have a type that is resistant to the antibiotic methicillin.
In the race to outsmart "untreatable" antibiotic-resistant gonorrhea, one of the three new treatments on the track is about to enter Phase 3 clinical trials. Hopefully, it'll be widely accessible sooner rather than later, for the 78 million people who are diagnosed with gonorrhea each year.
New research reveals how E. coli bacteria construct elaborate and effective tunnels to pump unwanted molecules like antibiotics and other toxins out of cells. The discovery could help us better understand how antibiotic resistance occurs and give us a leg-up to beat them at their own game.
The search is on to find antibiotics that will work against superbugs — bacteria that are rapidly becoming resistant to many drugs in our antibiotic arsenal.
Significant strides have been in the race to find antibiotics to treat superbug infections — those caused by bacteria resistant to the antibiotics used to treat them. Now, an international team of scientists has discovered a new antibiotic produced by a microbe found in Italian soil.
Yogurt is more than an excellent source of protein, calcium, and gut-healthy probiotic bacteria. A protein isolated from probiotic lactobacillus bacteria in yogurt is capable of inhibiting drug-resistant bacteria.
Joe McKenna died when he was 30 years old. A young married man with his future ahead of him, he was cleaning up the station where he worked as a fireman. Struck by a piece of equipment fallen from a shelf, Joe complained of a sore shoulder. Over the next week, Joe worsened and ended up in the hospital. Chilled, feverish, and delirious, his organs shut down from an infection we'd now call septic shock.
What do Leo Tolstoy (writer), Beethoven (composer), Paul Gaugin (artist), and Adolf Hitler (politician) have in common? They are all considered to have suffered from the sexually transmitted disease syphilis.
Bacteriotherapy sounds a lot more amenable of a term than "fecal transplant," yet they're both treatments that use bacteria itself to cure or treat infections. Fecal transplants, specifically, are an up-and-coming treatment option for a potentially deadly and difficult-to-treat diarrheal infection called Clostridium difficile.
As researchers from Yale searched our environment for compounds to aid in the battle against drug-resistant bacteria, they got an unlikely assist from ticks.
Wound infections don't usually enter the blood and become systemic, spreading the infection throughout our bodies, and there's a good reason for that: Our bodies actively work to prevent it, according to research that discovered a new use for a protein first discovered decades ago.
Drug-resistant bacteria have made curing some infections challenging, if not nearly impossible. By 2050, it's estimated that 10 million people will be dying annually from infections with antibiotic-resistant organisms.
Even though the Ebola virus was discovered as recently as 1976, over 30,000 people have been infected since, and half have died a horrible death. Since there's no way to cure the infection, the world desperately needs a way to prevent it — and the five similar viruses in its family, the ebolaviruses.
Long admired for their active and cooperative community behavior, some types of ants also wear a gardening hat. Nurturing underground fungus gardens, these ants have a win-win relationship that provides food for both ants and fungi. If we humans understand it better, it may just help us out, too.
A terrifying antibiotic-resistant superbug, one thought to only infect hospital patients, has made its debut in the real world. For the first time ever, the superbug carbapenem-resistant Enterobacteriaceae (CRE) infected six people who hadn't been in or around a hospital in at least a year, and researchers aren't sure how they got infected.
The bacteria Klebsiella pneumoniae is a bad actor known for being antibiotic-resistant and causing a variety of serious infections in hospitals, including pneumonia, surgical site wounds, and meningitis. K. pneumoniae is something you do not want to encounter if you have a compromised immune system.
Fighting fire with fire, scientists are harnessing the adaptability of helpful microbes to challenge the adaptability of deadly microbes. What are we talking about? Hunting with phages — viruses that attack and kill bacteria.
The evolution of our infection-fighting systems may have something to teach modern scientists. That's what a group from the University of Granada in Spain found when they studied a protein that's been around for over four billion years. Their work, by senior author José Sánchez-Ruiz and colleagues in the Department of Physical Chemistry, was published in the journal Cell Reports.
The noses of kids who live in areas of intense pig farming may harbor antibiotic-resistant bacteria, presumably acquired from the animals, according to a new study by scientists at the Johns Hopkins Bloomberg School of Public Health, UNC Gillings School of Global Public Health, and Statens Serum Institut in Denmark, published in Environmental Health Perspectives.
A 'superbug' fungus is currently running riot in the hospitals of New York and New Jersey. This outbreak of Candida auris has contributed to 17 deaths in NYC, according to recent reports.
On October 17, 1943, a story in the New York Herald Tribune read "Many laymen — husbands, wives, parents, brothers, sisters, friends — beg Dr. Keefer for penicillin," according to the American Chemical Society. Dr. Chester Keefer of Boston was responsible for rationing the new miracle drug, penicillin.
Our quest to find new antibiotics has taken a turn — a turn down the road, that is. A team of scientists from the University of Oklahoma is scooping up roadkill and searching for bacteria on them that might yield the world's next antibiotic.
Our quest to find novel compounds in nature that we can use against human diseases —a process called bioprospecting — has led a research team to a small frog found in India. From the skin slime of the colorful Hydrophylax bahuvistara, researchers reported finding a peptide — a small piece of protein — that can destroy many strains of human flu and can even protect mice against the flu.
Antibiotics used to prevent diseases in livestock are creating a world of hurt for humans and the soil we depend on for food. Bacterial resistance to antibiotics is a global health issue. The overuse, underuse, and poor use of these life-saving drugs is rapidly removing them as a treatment option for serious infections in humans—plus bacteria are naturally adaptive.
If you have encountered bed bugs lately, you are not alone. While the pesticides used to fight these pests are losing effectiveness, a fungus shows promise in knocking the bugs out of beds everywhere.
Usually, the mucus lining of the female genital tract presents a barrier that helps prevent infections. But, somehow, the bacteria that causes gonorrhea gets around and through that barrier to invade the female genital tract.
An advance in the race to stop birth defects caused by Zika-infected mothers has been made by a team of researchers from Rensselaer Polytechnic Institute in Troy, New York. They have identified the process Zika uses to gain entry into the placenta, and published their findings in the journal Biochemistry.
Hospitals are places we go to get well, and we don't expect to get sick or sicker there. But a study from researchers at the Cleveland Clinic, Case Western Reserve University School of Medicine, and Cleveland VA Medical Center in Ohio found that hospital floors in patient rooms were frequently contaminated with healthcare-associated pathogens—often dangerous multi-drug resistant bacteria.
Antibiotic-resistant infections that usually occur only in hospital settings are spreading in communities, increasing hospital stays—and danger—for young children.
Antibiotic use in infants has been associated with a host of childhood conditions later in life. Yet when an infection is suspected in a newborn, usually a sample of their blood is drawn to check for the presence of bacteria and 5 to 8 percent of them receive antibiotics while the diagnosis is pending.
As drug-resistant bacteria become more commonplace, researchers are looking for new antibacterial strategies to disrupt disease-causing microbes. Some scientists are working to create new drugs, while others are trying out drug combinations. Another group, however, are ditching pharmaceuticals altogether and experimenting with non-drug alternatives.
A rose by any other name may smell as sweet, but one annoying invasive weed may hold the answer to treating the superbug MRSA. Researchers from Emory University have found that the red berries of the Brazilian peppertree contain a compound that turns off a gene vital to the drug-resistance process.
We usually associate Salmonella bacteria with a dangerous type of food poisoning, but they actually are pretty good at seeking out tumors. That trait made the bacteria a great candidate to deliver a protein that would help knock tumors out.
Transmitted by a sandfly one-third the size of a mosquito, parasitic Leishmania protozoa are responsible for a flesh-destroying disease that kills an estimated 20,000 people per year. Two new studies offer understanding of how the parasite provides immunity through persistence and why some people suffer more virulent forms of the disease.
Scientists are constantly on the search for new organisms, species, and other types of life. A special group of these researchers, calling themselves "bioprospectors," dive deep into mines to find unique lifeforms with special properties not found anywhere else.
Although their effectiveness is waning, antibiotics remain a front-line defense against many infections. However, new science reveals using the wrong antibiotic for an infection could makes things much worse.
It hasn't even been eight years since Candida auris was discovered—cultured and identified from the ear canal of a patient in Japan—and now it's drug-resistant, setting up residence in hospitals, killing patients, and wreaking havoc across the globe.
Lighthouses and signal fires may have been the first social media. Without the ability to share language, a distant light meant "humans here." A new study from the University of California, San Diego, finds that bacteria can also send out a universal sign to attract the attention of their own, and other bacterial species.
Humanity is standing on an infection precipice. As antibacterial resistant grows, we're running out of options, and a recent scary case of total antibiotic resistance is a frighting view of our potential future. In the end, it was septic shock that took the life of a 70-year old woman with an incurable infection. One of few such cases in the US, her death could nonetheless be the shape of things to come.
No one can dispute the evolutionary success of bugs. The oldest insect fossils were found encased in crystallized mineral silica in Scotland in 1926, and they're between 396 and 407 million years old.
Cholera may be rare in the US, but cases of the disease have increased worldwide since 2005, particularly in Africa, southeast Asia, and Haiti. An estimated 3 to 5 million people are infected, and more than 100,000 die from the disease globally each year, mostly from dehydration.
A gold-medal winning entry into the iGEM synthetic biology competition could change the way we look at Esherichia coli, the bacteria better known as E. coli.
The story of Helicobacter pylori is a real testament to the tenacity of medical researchers to prove their hypothesis. It took decades before the scientific world would accept that the bacteria H. pylori caused ulcers.
